DEFINATION OF 2C-B PILL

Buy 2C-B online is a member of the 2C family of psychedelics. Alexander Shulgin was the first to synthesize it in 1974. The dose range is mentioned as 12–24 mg in Shulgin’s book PiHKAL. 2C-B is offered as a white powder that is occasionally pressed into pills or gel caps as a recreational drug. A number of street names are also used to refer to it such as pink cocaine, pills and more.

2,5-dimethoxy-4-bromophenethylamine (2C-B) is a psychedelic phenylethylamine derivative, structurally similar to mescaline. It is a serotonin 5-hydroxytryptamine-2A (5-HT_2A), 5-hydroxytryptamine-2B (5-HT_2B), and 5-hydroxytryptamine-2C (5-HT_2C) receptor partial agonist used recreationally as a new psychoactive substance. It has been reported that 2C-B induces mild psychedelic effects, although its acute pharmacological effects and pharmacokinetics have not yet been fully studied in humans. Sixteen healthy, experienced drug users self-administered an oral dose of 2C-B (10, 15, or 20 mg). Vital signs (blood pressure and heart rate) were measured at baseline 1, 2, 3, 4, and 6 hours (h).

Each participant completed subjective effects using three rating scales: the visual analog scale (VAS), the Addiction Research Centre Inventory (ARCI), and the Evaluation of the Subjective Effects of Substances with Abuse Potential (VESSPA-SSE) at baseline, 2–3 and 6 h after self-administration (maximum effects along 6 h), and the Hallucinogenic Rating Scale (maximum effects along 6 h).

Oral fluid (saliva) is collect to assess 2C-B and cortisol concentrations during 24 h. Acute administration of 2C-B increased blood pressure and heart rate. Scores of scales related to euphoria increased (high, liking, and stimulated), and changes in perceptions (distances, colors, shapes, and lights) and different body feelings/surrounding were produced. Mild hallucinating effects were described in five subjects. Maximum concentrations of 2C-B and cortisol were reached at 1 and 3 h after self-administration, respectively. Oral 2C-B at recreational doses induces a constellation of psychedelic/psychostimulant-like effects similar to those associated with serotonin-acting drugs.

light summary

Serotonergic hallucinogens (indolamines, e.g., psilocybin and LSD) and phenylethylamines [e.g., mescaline and 2,5-dimethoxy-4-iodoamphetamine (DOI)] have generally been divided into two types based on their chemical structure or primary mechanism of action (Vollenweider, 2001; Aarde and Taffe, 2017).

The 2C-series and its structural analogs, such as N-Benzylphenethylamines (NBOMes), are examples of new psychedelics (Tracy et al., 2017). They’re all phenylethylamine derivatives with methoxy substitutions at the 2 and 5 positions obtained from the two carbon molecules between the benzene ring and the amino group, and they’re all structurally similar to mescaline. Nexus (2C-B, 2,5-dimethoxy-4-bromophenethylamine) is one of the most well-known 2C-type medicines.

2c-b Dosage

Dosage will depend on a number of factors including tolerance, gender and how it’s taken (either nasally or orally). This is a guide only.

• Threshold – 2-5 mg
• Light – 5-15 mg
• Common – 15-25 mg
• Strong – 25 mg +

2C-B is highly dose sensitive. Lower doses will be more MDMA-like, higher doses will produce a full psychedelic experience.  Taking doses over 25 mg will greatly increase the risk of having a bad trip.